发明名称 |
Anti-tumor antibody-tumor suppressor fusion protein compositions and methods of use for the treatment of cancer |
摘要 |
The present invention is directed to methods and compositions for treating cancer, including, hematologic malignancies, such as B-cell malignancies, with anti-tumor antibody-tumor suppressor fusion proteins in order to selectively restore tumor suppressor gene function to cancer cells in which such tumor suppressor gene function has been lost. The present invention is also directed to methods and compositions for diagnosing cancer and for predicting and assessing response to treatment. |
申请公布号 |
AU2012240002(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
AU20120240002 |
申请日期 |
2012.04.06 |
申请人 |
MEMORIAL SLOAN-KETTERING CANCER CENTER |
发明人 |
WENDEL, HANS-GUIDO;ORCCHIO, ELISA |
分类号 |
C07K14/435;A61K47/48;C12N15/62;G01N33/574 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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