发明名称 |
Novel protein purification methods |
摘要 |
The invention provides methods of reducing fouling of ultrafiltration membranes in processes wherein virus particles are removed from aqueous solutions comprising virus particles and at least one protein by adding a surfactant or non-surfactant, non-ionic agent to the aqueous solution prior to filtration. The invention also provides methods to dissociate protein aggregates or to reduce the formation of protein aggregates by adding a surfactant or non- surfactant, non- ionic agent to the protein solution. |
申请公布号 |
AU2012237026(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
AU20120237026 |
申请日期 |
2012.03.23 |
申请人 |
GENENTECH, INC. |
发明人 |
BROWN, ARICK;JI, JUNYAN;LIU, JUN;WANG, YUCHANG JOHN |
分类号 |
C12N7/02 |
主分类号 |
C12N7/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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