Methods and uses for molecular tags are disclosed. Molecular tags may be attached to nucleic acid molecules. The attachment of the nucleic acid molecules prior to PCR amplification and sequencing improves the accuracy of genetic analysis and detection of genetic variations and diversity. Molecular tags may also be used for detection of drug-resistant variants. Methods for using molecular tags for determining and correcting PCR errors and/or sequencing error are also disclosed.
申请公布号
WO2013130512(A3)
申请公布日期
2013.10.24
申请号
WO2013US27891
申请日期
2013.02.27
申请人
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
发明人
JABARA, CASSANDRA, B.;ANDERSON, JEFFREY, A.;SWANSTROM, RONALD, I.