IL-22 AS A PROGNOSTIC AND DIAGNOSTIC MARKER IN RHEUMATOID ARTHRITIS
摘要
The present invention relates to interleukin-22 (IL-22) for use as a prognostic marker for bone erosion associated with rheumatoid arthritis (RA) and for use as a diagnostic marker for the progression of RA. It further relates to a method of prognosing the development of bone erosion associated with rheumatoid arthritis (RA), to a method of diagnosing the progression of RA and to the use of an IL-22-specific test kit for prognosing the development of bone erosion or diagnosing the progression of rheumatoid arthritis in a subject suffering from RA.
申请公布号
WO2012116809(A9)
申请公布日期
2013.10.24
申请号
WO2012EP00876
申请日期
2012.02.29
申请人
LUDWIG-MAXIMILIANS UNIVERSITAET MUENCHEN;SCHULZE-KOOPS, HENDRIK;SKAPENKO, ALLA;LEIPE, JAN