发明名称 |
PLANT PROFILIN POLYPEPTIDES FOR USE IN NON-SPECIFIC ALLERGY IMMUNOTHERAPY |
摘要 |
<p>The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.</p> |
申请公布号 |
CA2870399(A1) |
申请公布日期 |
2013.10.24 |
申请号 |
CA20132870399 |
申请日期 |
2013.04.16 |
申请人 |
ALK-ABELLO A/S |
发明人 |
LUND, KAARE;BRIMNES, JENS;HENMAR, HELENE;IPSEN, HANS-HENRIK;MÆRKEDAHL, LISE LUND;HANSEN, GITTE NORDSKOV;MONSALVE CLEMENTE, RAFAEL IGNACIO |
分类号 |
A61K39/35;A61K39/36;C07K14/415 |
主分类号 |
A61K39/35 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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