发明名称 Rational design of components of the oligo-saccharyltransferase-catalysed asparagine-linked glycosylation
摘要 The present invention is directed to methods for identifying or designing (a) a potential oligosaccharide donor, (b) a potential oligosaccharyltransferase (OST), (c) a potential consensus sequence motif polypeptide, and/or (d) a potential glycosylation inhibitor for use in the oligosaccharyltransferase (OST)-catalysed asparagine-linked ("N-linked") glycosylation, comprising the steps of generating a three-dimensional model of the catalytic domain and/or the polypeptide binding site of the oligosaccharyltransferase (OST) of
申请公布号 AU2012251886(A1) 申请公布日期 2013.10.24
申请号 AU20120251886 申请日期 2012.05.03
申请人 ETH ZURICH 发明人 AEBI, MARKUS;LOCHER, KASPAR;LIZAK, CHRISTIAN
分类号 C12Q1/48 主分类号 C12Q1/48
代理机构 代理人
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