Disclosed are the ERK inhibitors of formula 1.0: (Formula (A1)), and the pharmaceutically acceptable salts, esters and solvates thereof. Q is a piperidine ring that can have a bridge or a fused ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula A1.
申请公布号
EP2483263(A4)
申请公布日期
2013.10.23
申请号
EP20100821040
申请日期
2010.09.20
申请人
MERCK SHARP & DOHME CORP.
发明人
ZHU, HUGH, Y.;DESAI, JAGDISH, A.;COOPER, ALAN, B.;DOLL, RONALD, J.
