发明名称 RADIOPAQUE IODINATED PRODUCTS INTENDED FOR USE MEDICAL IMAGING AND THEIR METHODS OF PREPARATION
摘要 Iodinated amphiphilic compound of formula (I): AG1-X-R(I) wherein AG1 represents an unsaturated (C8-C52) aliphatic hydrocarbon chain found in fatty acids having specific location of double bonds, the chain including at least one iodine atom directly linked to a carbon atom of a non-conjugated double bond by a covalent link, the second carbon atom of the double bond bearing a halogen atom different from a iodine atom, X represents a polyethylene glycol including 1 to 50 ethylene glycol groups, R represents a hydrogen atom or a group AG2 being identical to or different from AG1, AG1, X, R and AG2 being selected so that the amphiphilic compound has a hydrophilic/lipohilic balance included between 4 and 30.
申请公布号 EP2651455(A1) 申请公布日期 2013.10.23
申请号 EP20110802034 申请日期 2011.12.13
申请人 UNIVERSITE DE STRASBOURG 发明人 HALLOUARD, FRANCOIS;ANTON, NICOLAS;ZUBER, GUY;VANDAMME, THIERRY;CONSTANTINESCO, ANDRE;CHOQUET, PHILIPPE
分类号 A61K49/04 主分类号 A61K49/04
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