| 发明名称 |
GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY |
| 摘要 |
<p>The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.</p> |
| 申请公布号 |
EP2318427(B1) |
申请公布日期 |
2013.10.23 |
| 申请号 |
EP20090780232 |
申请日期 |
2009.07.07 |
| 申请人 |
NICOX S.A. |
发明人 |
BENEDINI, FRANCESCA;BONFANTI, ANNALISA;CHIROLI, VALERIO;STEELE, REBECCA;ONGINI, ENNIO;BIONDI, STEFANO |
| 分类号 |
C07J41/00;A61K31/573;A61P5/44;A61P27/02;C07J71/00 |
主分类号 |
C07J41/00 |
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