| 发明名称 |
NOVEL N-(4-(AZETIDINE-1-CARBONYL)PHENYL)-(HETERO-)ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS |
| 摘要 |
<p>Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.</p> |
| 申请公布号 |
EP2651898(A1) |
申请公布日期 |
2013.10.23 |
| 申请号 |
EP20110808773 |
申请日期 |
2011.12.16 |
| 申请人 |
AGIOS PHARMACEUTICALS, INC.;YAN, SHUNQI |
发明人 |
SALITURO, FRANCESCO G.;SAUNDERS, JEFFREY O.;YAN, SHUNQI |
| 分类号 |
C07D215/36;A61K31/397;A61P35/00;C07D401/12 |
主分类号 |
C07D215/36 |
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