发明名称 |
Compositions and methods for detection of colorectal cancer |
摘要 |
We have identified a new variant of ileal bile acid binding protein (IBABP), designated IBABP-L, which is a biomarker for colorectal cancer. The transcript for IBABP-L arises from an alternative start site and includes three exons that are absent in IBABP. IBABP-L also shares part of a fourth exon with IBABP. The protein encoded by IBABP-L contains a deduced 49 residue N-terminal sequence that is not found in the IBABP protein. The present invention provides methods for diagnosing colorectal cancer and other compositions and methods based on this discovery.
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申请公布号 |
US8563248(B2) |
申请公布日期 |
2013.10.22 |
申请号 |
US20100959349 |
申请日期 |
2010.12.02 |
申请人 |
SMITH JEFFREY W.;FANG CHANGMING |
发明人 |
SMITH JEFFREY W.;FANG CHANGMING |
分类号 |
C07H21/04;C12Q1/68 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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