发明名称 |
SYNTHESIS OF DEOXYBIOTINYL HEXAMETHYLENEDIAMINE-DOTA |
摘要 |
A process for the synthesis of deoxybiotinyl hexamethylenediamine-DOTA is herein described. Said process comprises reacting biotinyl hexamethylenediamine with tri-t-butyl-DOTA in the presence of benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate, as the condensing agent, and triethylamine, as the base.
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申请公布号 |
CA2607262(C) |
申请公布日期 |
2013.10.22 |
申请号 |
CA20062607262 |
申请日期 |
2006.05.31 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. |
发明人 |
MARZI, MAURO;DI MARZO, MARIA |
分类号 |
C07D495/04 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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地址 |
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