发明名称 LOW-TEMPERATURE SYNTHESIS OF METHYLPHENIDATE HYDROCHLORIDE
摘要 <p>The present invention describes a process for the preparation of methylphenidate hydrochloride. The process involves the esterification of ritalinic acid and methanol in the presence of an acid catalyst at a low temperature. The process may optionally involve the addition of an orthoester.</p>
申请公布号 KR20130115322(A) 申请公布日期 2013.10.21
申请号 KR20137018653 申请日期 2011.12.16
申请人 RHODES TECHNOLOGIES 发明人 HUNTLEY C. FREDERICK M.;KATAISTO ERIK WAYNE;LA LUMIERE KNICHOLAUS DUDLEY;REISCH HELGE ALFRED
分类号 C07D211/40;A61K31/4458;A61P25/00 主分类号 C07D211/40
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