发明名称 |
LOW-TEMPERATURE SYNTHESIS OF METHYLPHENIDATE HYDROCHLORIDE |
摘要 |
<p>The present invention describes a process for the preparation of methylphenidate hydrochloride. The process involves the esterification of ritalinic acid and methanol in the presence of an acid catalyst at a low temperature. The process may optionally involve the addition of an orthoester.</p> |
申请公布号 |
KR20130115322(A) |
申请公布日期 |
2013.10.21 |
申请号 |
KR20137018653 |
申请日期 |
2011.12.16 |
申请人 |
RHODES TECHNOLOGIES |
发明人 |
HUNTLEY C. FREDERICK M.;KATAISTO ERIK WAYNE;LA LUMIERE KNICHOLAUS DUDLEY;REISCH HELGE ALFRED |
分类号 |
C07D211/40;A61K31/4458;A61P25/00 |
主分类号 |
C07D211/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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