发明名称 SELECTIVE GLYCOSIDASE INHIBITOR AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To provide compounds for selectively inhibiting glycosidases, prodrugs of the compounds, uses of the compounds or prodrugs, pharmaceutical compositions including the compounds or prodrugs of the compounds, and methods of treating diseases or disorders related to deficiency or overexpression of O-GlcNAcase, accumulation or deficiency of O-GlcNAc.SOLUTION: The invention provides compounds of formula (I) for selectively inhibiting glycosidases, prodrugs of the compounds, and pharmaceutical compositions including the compounds or prodrugs of the compounds.
申请公布号 JP2013213037(A) 申请公布日期 2013.10.17
申请号 JP20130123917 申请日期 2013.06.12
申请人 SIMON FRASER UNIV 发明人 VOCADLO DAVID;MCEACHERN ERNEST;WHITWORTH GARRETT;MACAULEY MATTHEW;HEINONEN JULIA;STUBBS KEITH;LI TONG-SHUANG
分类号 C07H9/06;A61K31/7042;A61P1/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P25/04;A61P25/08;A61P27/02;A61P29/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C12N9/99 主分类号 C07H9/06
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