发明名称 NOVEL SUBSTITUTED TRIAZOLYL PIPERAZINE AND TRIAZOLYL PIPERIDINE DERIVATIVES AS GAMMA SECRETASE MODULATORS.
摘要 <p>The present invention is concerned with novel substituted triazolyl piperazine and triazolyl piperidine derivatives of Formula (I) wherein R<sup>1</sup>, R<sup>2</sup>, R<sup>3</sup>, R<sup>4a</sup>, R<sup>4b</sup>, R<sup>5</sup>, X, Y<sup>1</sup>, Y<sup>2</sup>, L<sup>1</sup>, and L<sup>2</sup> have the meaning defined in the claims. The compounds according to the present invention are useful as gamma secretase modulators. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament.</p>
申请公布号 MX2013010970(A) 申请公布日期 2013.10.17
申请号 MX20130010970 申请日期 2012.03.22
申请人 CELLZOME LIMITED 发明人 VAN BRANDT, SVEN FRANCISCUS ANNA;BISCHOFF, FRANCOIS PAUL;BERTHELOT, DIDIER JEAN-CLAUDE;VELTER, ADRIANA INGRID
分类号 C07D249/10;A61K31/4196 主分类号 C07D249/10
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