发明名称 |
ORAL FILM CONTAINING OPIATE ENTERIC-RELEASE BEADS |
摘要 |
<p>A control release and abuse-resistant opiate drug delivery oral wafer or edible oral film dosage to treat pain and substance abuse is provided. The drug delivery oral wafer or edible oral film dosage includes a controlled release layer containing enteric-release beads dispersed in a polymer matrix. The enteric-release beads are formed from a therapeutic amount of an opioid agonist and/or pharmaceutically acceptable salt thereof and a sub- therapuetic amount of opioid antagonist and/or pharmaceutically acceptable salt thereof coated or encapsulated in an enteric-release polymer. The controlled release polymer matrix dissolves or disintegrates following administration or consumption of the oral wafer or edible oral film, releasing the enteric-release beads to be swallowed, with subsequent absorption of the active ingredients within the patient's intestines.</p> |
申请公布号 |
CA2869450(A1) |
申请公布日期 |
2013.10.17 |
申请号 |
CA20132869450 |
申请日期 |
2013.04.11 |
申请人 |
LTS LOHMANN THERAPIE-SYSTEME AG |
发明人 |
LI, MICHAEL HSIN CHWEN |
分类号 |
A61K9/00;A61K9/16;A61K31/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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