发明名称 GENETIC VARIATIONS IN THE INTERLEUKIN-6 RECEPTOR GENE AS PREDICTORS OF THE RESPONSE OF PATIENTS TO TREATMENT WITH INTERLEUKIN-6 RECEPTOR INHIBITORS
摘要 The present invention relates to a method for predicting the response of patients to treatment with Interleukin-6 Receptor (IL6R) inhibitors, such as antibodies directed against the IL6R. The method comprises the analysis of one or more genetic variations, in particular single nucleotide polymorphisms, in or associated with the Interleukin-6 Receptor gene. The present invention further relates to a kit for use in predicting the response of patients to treatment with IL6R inhibitors, such as Tocilizumab. The patients suffers from rheumatoid arthritis.
申请公布号 US2013274133(A1) 申请公布日期 2013.10.17
申请号 US201113877290 申请日期 2011.09.30
申请人 NIELSEN CLAUS HENRIK;ENEVOLD CHRISTIAN;RIGSHOSPITALET 发明人 NIELSEN CLAUS HENRIK;ENEVOLD CHRISTIAN
分类号 C12Q1/68;A61K39/395 主分类号 C12Q1/68
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