发明名称 MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS.
摘要 The present invention discloses compounds of Formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof: Formula (I) which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 MX2013003230(A) 申请公布日期 2013.10.17
申请号 MX20130003230 申请日期 2011.09.20
申请人 ENANTA PHARMACEUTICALS, INC. 发明人 BIN WANG;YAT SUN OR;GUOQIANG WANG;JUN MA;JIANG LONG
分类号 A61K38/21 主分类号 A61K38/21
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