| 发明名称 |
HUMANIZED MONOCLONAL ANTIBODIES AND METHODS OF USE |
| 摘要 |
The present invention comprises a humanized monoclonal antibody that binds to the human immunoglobulin heavy chain variable region germline gene VH1-69. This antibody is derived from Mab G6 and recognizes the same epitope. Moreover, the antibody is used in combination with vaccines to augment an immune response to the antigen. |
| 申请公布号 |
EP2575882(A4) |
申请公布日期 |
2013.10.16 |
| 申请号 |
EP20110790430 |
申请日期 |
2011.06.02 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
SUI, JIANHUA;AVNIR, YUVAL;MARASCO, WAYNE |
| 分类号 |
C07K16/42;A61K39/00;A61K39/145;A61K39/395;C07K16/10;C12P21/08 |
主分类号 |
C07K16/42 |
| 代理机构 |
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