发明名称 |
MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF |
摘要 |
Multifunctional nitroxide derivatives comprising a potassium channel opener and a reactive oxygen species (ROS) degradation catalyst that can act as an anti-oxidant, as well as pharmaceutical compositions comprising them are provided. The multifunctional compounds and pharmaceutical compositions are useful for treatment of diseases, disorders or conditions associated with oxidative stress or endothelial dysfunction. |
申请公布号 |
EP2649048(A1) |
申请公布日期 |
2013.10.16 |
申请号 |
EP20110808945 |
申请日期 |
2011.12.08 |
申请人 |
RADIKAL THERAPEUTICS INC. |
发明人 |
JAGTAP, PRAKASH;SALZMAN, ANDREW LURIE |
分类号 |
C07D207/46;A61K31/40;A61K31/4427;A61K31/4439;A61K31/444;A61K31/4468;A61K31/55;A61P9/10;A61P25/28;A61P39/00;C07D211/94;C07D223/12;C07D401/12 |
主分类号 |
C07D207/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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