发明名称 DIMERIC MOLECULAR COMPLEXES WITH FREE CYSTEINE RESIDUES AND CONJUGATES THEREOF
摘要 <p>The invention relates generally to dimeric molecular complexes comprising two fusion proteins. Each fusion protein comprises a biological effector moiety, a polypeptide spacer sequence, and an IgE CH4 dimerization domain. The dimeric molecular complexes may be conjugated, at a defined site, to other molecules including drug moieties, cytotoxic agents, labels (such as detectable labels), or biocompatible polymers.</p>
申请公布号 EP2648751(A2) 申请公布日期 2013.10.16
申请号 EP20110846369 申请日期 2011.12.07
申请人 BAYER HEALTHCARE LLC 发明人 LIGHT, DAVID;SZYMANSKI, PAUL;SETO, MARIAN;CORNELIUS, ALINE
分类号 A61K39/395;A61K47/48;C07K16/00;C07K16/18 主分类号 A61K39/395
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