发明名称 COMBINATIONS OF AROMATASE INHIBITORS AND ANTIOXIDANTS
摘要 Pharmaceutical medication comprises an aromatase- inhibitor and antioxidants as active ingredients different from the aromatase- inhibitor. An independent claim is also included for a pharmaceutical composition comprising the aromatase inhibitor and a lipoic acid and/or green tea extract polyphenols, preferably OM24(RTM: Blend of all-natural ingredients containing polyphenols). ACTIVITY : Cytostatic; Endocrine-Gen. MECHANISM OF ACTION : The ability of the medication to treat breast cancer was tested in a 59-year-old patient diagnosed with estrogen receptor-positive (ER-positive) tumor in the right breast, where the patient was topically applied with a cream based formulation comprising alpha -lipoic acid (0.5%) and 4-hydroxyandrostendione (1.5%) for 29 days, 2 times daily. The result showed that the medication reduced the tumor volume by 78.5%.
申请公布号 EP2648721(A1) 申请公布日期 2013.10.16
申请号 EP20120703265 申请日期 2012.01.30
申请人 LUCOLAS-M.D. LTD. 发明人 SCHMIDT, ALFRED
分类号 A61K31/352;A61K31/385;A61K31/568;A61K31/5685;A61K36/82;A61P35/00 主分类号 A61K31/352
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