| 发明名称 |
FUSED PYRIMIDINES AS AKT INHIBITORS |
| 摘要 |
<p>The present invention relates to compounds of formula (I), a N-oxide or tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the imidazole to which it is fused, R4, R6, R7, R10, m and n have the meanings as given in the description and the claims, which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.</p> |
| 申请公布号 |
EP2396331(B1) |
申请公布日期 |
2013.10.16 |
| 申请号 |
EP20100703022 |
申请日期 |
2010.02.05 |
| 申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
VENNEMANN, MATTHIAS;BAER, THOMAS;MAIER, THOMAS;HOELDER, SWEN;BENEKE, GERRIT;DEHMEL, FLORIAN;ZUELCH, ARMIN;STRUB, ANDREAS;BECKERS, THOMAS;INCE, STUART;REHWINKEL, HARTMUT;LIU, NINGSHU;BOEMER, ULF |
| 分类号 |
C07D487/04;A61K31/517;A61P35/00 |
主分类号 |
C07D487/04 |
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