发明名称 |
High throughput screens for small-molecule inhibitors of the nuclear receptor-like pathway regulating multidrug resistance in fungi |
摘要 |
The present invention relates to the identification of molecular mechanisms associated with multidrug resistance (MDR) in fungal infections. More specifically, fungi harbor a nuclear receptor-like pathway controlling MDR, which represents a novel therapeutic target for the treatment of MDR in pathogenic fungi such as C. glabrata.
|
申请公布号 |
US8557746(B2) |
申请公布日期 |
2013.10.15 |
申请号 |
US20100751517 |
申请日期 |
2010.03.31 |
申请人 |
NAAR ANDERS M.;WAGNER GERHARD;NISHIKAWA JOY;ARTHANARI HARIBABU;THE GENERAL HOSPITAL CORPORATION;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
NAAR ANDERS M.;WAGNER GERHARD;NISHIKAWA JOY;ARTHANARI HARIBABU |
分类号 |
C40B30/04;C40B30/10 |
主分类号 |
C40B30/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|