发明名称 |
Compositions and methods for treatment and prevention of insulin resistance |
摘要 |
Disclosed herein are methods of delaying the onset or treating diabetes that comprises administering a uric acid lowering agent. The inventors have made the remarkable discovery that elevated uric acid levels are not a corollary to insulin resistance, but rather a primary mediator of insulin resistance. Specifically exemplified are methods that involve administering to a patient susceptible to development of diabetes a composition comprising a uric acid lowering agent in a regimen that maintains serum uric acid levels below at least 5.2 to 5.5 mg/dl.
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申请公布号 |
US8557831(B2) |
申请公布日期 |
2013.10.15 |
申请号 |
US20050572270 |
申请日期 |
2005.07.21 |
申请人 |
JOHNSON RICHARD J.;NAKAGAWA TAKAHIKO;UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
JOHNSON RICHARD J.;NAKAGAWA TAKAHIKO |
分类号 |
A01N43/90 |
主分类号 |
A01N43/90 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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