发明名称 |
Depsipeptider og deres terapeutiske anvendelse |
摘要 |
<p>The subject application pertains to a compound of structure IX or X: or a pharmaceutically acceptable salt thereof, wherein: X is -C(=O)N(R10)- or -CH(OPr3) -; R7, R9 and R10 are the same or different and represent hydrogen or an amino acid side chain moiety from either a natural or an unnatural amino acid; Pr1 and Pr2 are the same or different and represent hydrogen or a thiol protecting group; Pr3 is hydrogen or an alcohol protecting group; R1, R2, R5 and R6 are the same or different and represent hydrogen or an amino acid side chain moiety from either a natural or an unnatural amino acid, or R1 and R2 and/or R5 and R6, taken together with the carbon atom to which they are attached, form a spirocyclic moiety, with the proviso that: each of R1 and R2 is not hydrogen, or each of R5 and R6 is not hydrogen.</p> |
申请公布号 |
DK2293846(T3) |
申请公布日期 |
2013.10.14 |
申请号 |
DK20090750136T |
申请日期 |
2009.05.22 |
申请人 |
KARUS THERAPEUTICS LIMITED |
发明人 |
SHUTTLEWORTH, STEPHEN, JOSEPH;SILVA, FRANCK, ALEXANDRE;TOMASSI, CYRILLE, DAVY;CECIL, ALEXANDER, RICHARD, LIAM;HILL, THOMAS, JAMES |
分类号 |
A61P35/00;C07K5/02;C07K5/10 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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