发明名称 |
Compuestos derivados de (1,8) naftiridinas 2,4 diaril sustituidas inhibidores de quinasas; su procedimiento de obtencion; composicion farmaceutica; y su uso para el tratamiento y/o prevencion de cancer, tumor, tumores malignos, entre otros; kit farmaceutico. |
摘要 |
The present invention relates to novel [1,8]naphthyridine derivatives of formula (I) and to the use of such compounds in which the inhibition, regulation and/or modulation of signal transduction by ATP consuming proteins like kinases plays a role, particularly to inhibitors of TGF-beta receptor kinases, and to the use of such compounds for the treatment of kinase-induced diseases, in particular for the treatment of tumors. |
申请公布号 |
CL2012003680(A1) |
申请公布日期 |
2013.10.11 |
申请号 |
CL20120003680 |
申请日期 |
2012.12.26 |
申请人 |
MERCK PATENT GMBH |
发明人 |
DORSCH DIETER;JONCZYK ALFRED;HOELZEMANN GUENTER;AMENDT CHRISTIANE;ZENKE FRANK |
分类号 |
C07D471/04;A61K31/4375;A61P35/00;C07D519/00 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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