发明名称 A BENZIMIDAZOLE DERIVATIVE AS A CALCIUM CHANNEL BLOCKER
摘要 The invention relates to compounds of formula (I) wherein R1 represents aryl, which is unsubstituted, or mono-, di-, or tri-substituted wherein the substituents are independently selected from the group consisting of (C1-4)alkyl, (C1-4)alkoxy, halogen, and trifluoromethyl; R2 represents hydrogen, or —CO—R21; R21 represents (C1-5)alkyl, (C1-3)fluoroalkyl, or (C3-6)cycloalkyl; m represents the integer 2, or 3; p represents the integer 2 or 3; and R3 represents hydrogen, or (C1-5)alkyl; and pharmaceutically acceptable salts of such compounds. These compounds are useful as calcium channel blockers.
申请公布号 HK1155739(A1) 申请公布日期 2013.10.11
申请号 HK20110109943 申请日期 2011.09.21
申请人 ACTELION PHARMACEUTICALS LTD 发明人 HUBLER, FRANCIS;HILPERT, KURT;RENNEBERG, DORTE
分类号 C07D;A61K;A61P 主分类号 C07D
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