发明名称 |
EXPRESSION OF CYTOSOLIC MALIC ENZYME IN TRANSGENIC YARROWIA TO INCREASE LIPID PRODUCTION |
摘要 |
Transgenic Yarrowia species are disclosed herein that comprise a polynucleotide encoding a cytosolic malic enzyme, a lipid content that is at least about 35% by weight of the dry cell weight of the Yarrowia species, and an engineered polyunsaturated fatty acid (PUFA) biosynthetic pathway, wherein overexpression of the cytosolic malic enzyme increases lipid content. |
申请公布号 |
WO2013151738(A1) |
申请公布日期 |
2013.10.10 |
申请号 |
WO2013US31839 |
申请日期 |
2013.03.15 |
申请人 |
E. I. DU PONT DE NEMOURS AND COMPANY |
发明人 |
MACOOL, DANIEL,, JOSEPH;ZHU, QUINN QUN;XUE, ZHIXIONG |
分类号 |
C12N1/19;C12N9/04;C12P7/64 |
主分类号 |
C12N1/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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