| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers medicine, namely to preparing biological hydroxyapatite. What is described is a method for preparing biological hydroxyapatite involving pre-cleaning of bones, grinding, dissolving of bone tissue in hydrochloric acid, hydroxyapatite precipitation using a precipitant, filtration, heat treatment and deposit grinding; bones are ground to a particle size of 2.5-5 cm; bone tissue is dissolved hydrochloric acid of the concentration of 0.5-2M; that is followed by separating a liquid fraction of the suspension by filtration with the filtered solution added with chitosan of the concentration of 1.5-2 wt % at constant mixing until completely dissolved. The hydroxyapatite precipitant is 3-5M sodium hydroxide or potassium hydroxide added at constant mixing to ensure pH 7.0-7.5 of the reaction mixture; the filtered precipitation is heat treated by calcination at temperature 830°C for at least 40 minutesEFFECT: fine hydroxyapatite powder of the particle size of 5 nm having the composition of microelements being as close as possible to that of human bone tissue.1 cl |
