| 摘要 |
PROBLEM TO BE SOLVED: To provide kit of parts comprising a nucleic acid sequence encoding a permease and a drug comprising one nucleobase moiety or a precursor thereof.SOLUTION: The invention relates to kit of parts comprising a nucleic acid sequence comprising a precursor of a drug comprising a gene coding a purine or a cytosine permease of S. Cerevisiae, and a suicide gene comprising a first nucleic acid sequence selected from the group consisting of upp, FUR1 and FUR1&Dgr;105, and a second nucleic acid sequence selected from the group consisting of CodA and FCY1. The invention also relates to a vector comprising a gene coding a permease and a suicide gene. |
