发明名称 NOVEL COMPOUND, METHOD FOR PRODUCING SAME AND ANTITUMOR AGENT
摘要 Provided are: a novel compound which has excellent cytotoxic activity; and an antitumor agent. Also provided is a method for easily and simply producing the novel compound. Provided are: a compound represented by one of formulae (1)-(4); and an antitumor agent which contains the compound as an active ingredient. In formulae (1)-(4), each of R1-R9 represents an alkyl group or the like; R10 represents a -C(O)ORd group, a -C(O)NReRf group or the like; and each of Rd, Re and Rf independently represents an alkyl group or the like. With respect to formula (1), the cases where R1, R3, R6 and R9 are methyl groups, R4, R5, R7 and R8 are hydrogen atoms, R2 is a hydroxy group and R10 is a methyl ester group or the like are excluded.
申请公布号 WO2013151161(A1) 申请公布日期 2013.10.10
申请号 WO2013JP60487 申请日期 2013.04.05
申请人 TOKYO UNIVERSITY OF SCIENCE FOUNDATION;JAPANESE FOUNDATION FOR CANCER RESEARCH 发明人 SHIINA, ISAMU;YAMORI, TAKAO
分类号 C07D213/40;A61K31/4406;A61P35/00;C07C29/147;C07C33/02;C07C327/22;C07F7/18 主分类号 C07D213/40
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