发明名称 1,2- PYRIDAZINE, 1,6- PYRIDAZINE OR PYRIMIDINE - BENZAMIDE DERIVATIVES AS GPBAR1 MODULATORS
摘要 <p>This invention relates to novel 1,2-pyridazines, 1,6-pyridazines or pyrimidines of the formula I wherein B1 to B3 and R1 to R7 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and may therefore be useful as medicaments for the treatment of diseases such as type II diabetes.</p>
申请公布号 WO2013149977(A1) 申请公布日期 2013.10.10
申请号 WO2013EP56849 申请日期 2013.04.02
申请人 F. HOFFMANN-LA ROCHE AG;DEHMLOW, HENRIETTA;ERICKSON, SHAWN DAVID;MATTEI, PATRIZIO;RICHTER, HANS 发明人 DEHMLOW, HENRIETTA;ERICKSON, SHAWN DAVID;MATTEI, PATRIZIO;RICHTER, HANS
分类号 C07D401/04;A61K31/50;A61K31/505;A61P3/00;A61P29/00;C07D237/20;C07D239/42 主分类号 C07D401/04
代理机构 代理人
主权项
地址