发明名称 |
HETEROBICYCLIC COMPOUNDS AS BETA-LACTAMASE INHIBITORS |
摘要 |
The present invention is directed to compounds which are beta-lactamase inhibitors. The compounds and their pharmaceutically acceptable salts, are useful in combination with beta-lactam antibiotics, or alone, for the treatment of bacterial infections, including infections caused by drug resistant organisms, including multi-drug resistant organisms. The present invention includes compounds according to formula (Ia): or a pharmaceutically acceptable salt thereof, wherein the values of R1, R 2, R 3 and R 4 are described herein. |
申请公布号 |
CA2866467(A1) |
申请公布日期 |
2013.10.10 |
申请号 |
CA20132866467 |
申请日期 |
2013.04.02 |
申请人 |
ASTRAZENECA AB |
发明人 |
MCGUIRE, HELEN;BIST, SHANTA;BIFULCO, NEIL;ZHAO, LIANG;WU, YE;HUYNH, HOAN;XIONG, HUI;COMITA-PREVOIR, JANELLE;DUSSAULT, DAEMIAN;GENG, BOLIN;CHEN, BRENDAN;DURAND-REVILLE, THOMAS;GULER, SATENIG |
分类号 |
C07D471/08;A61K31/439;A61P31/04 |
主分类号 |
C07D471/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|