| 发明名称 |
MANIPULATION OF STEM CELL FUNCTION BY P53 ISOFORMS |
| 摘要 |
This invention provides methods and compositions for increasing the efficiency of obtaining pluripotent stem cells, the method comprising expressing a 133p53 in cells that are being re-programmed to obtain pluripotent cells. The invention also provides method of inhibiting the proliferation of cancer stem cells, the method comprising suppressing expression of 133p53 in the cells.
|
| 申请公布号 |
US2013267029(A1) |
申请公布日期 |
2013.10.10 |
| 申请号 |
US201113877100 |
申请日期 |
2011.09.30 |
| 申请人 |
HARRIS CURTIS C.;HORIKAWA IZUMI;FUJITA KAORI;MONDAL ABDUL M.;PARK KYE-YOON;PINE SHARON R.;SERRANO MANUEL;FUNDACION CENTRO NACIONAL DE IVESTIGACIONES ONCOLOGICAS, CARLOS;THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALT |
发明人 |
HARRIS CURTIS C.;HORIKAWA IZUMI;FUJITA KAORI;MONDAL ABDUL M.;PARK KYE-YOON;PINE SHARON R.;SERRANO MANUEL |
| 分类号 |
C12N15/85 |
主分类号 |
C12N15/85 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
