发明名称 CYTOTOXICITY-INDUCING THERAPEUTIC AGENT
摘要 <p>By replacing the antigen-binding domain, the present inventors discovered novel polypeptide complexes that retain BiTE's strong anti-tumor activity and excellent safety properties, as well as have long half-life in blood and can damage various different target cells.</p>
申请公布号 EP2647707(A1) 申请公布日期 2013.10.09
申请号 EP20110845786 申请日期 2011.11.30
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 NEZU, JUNICHI;ISHIGURO, TAKAHIRO;NARITA, ATSUSHI;SAKAMOTO, AKIHISA;KAWAI, YUMIKO;IGAWA, TOMOYUKI;KURAMOCHI, TAICHI
分类号 C12N15/09;A61K39/395;A61P35/00;C07K16/28;C07K16/30;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10 主分类号 C12N15/09
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