发明名称 |
IMPROVED LIGHT-EMITTING MOLECULES |
摘要 |
<p>Disclosed are luciferase polypeptides with improved light-emitting activity and their encoding nucleic acids. These molecules are useful in a range of assays including luciferase-based gene reporter assays, bioluminescence resonance energy transfer assays, protein complementation assays and other applications in which luciferase enzymes are utilized as detectable and/or quantifiable labels. Also disclosed are methods and compositions for increasing the sensitivity and/or improving the kinetics of luciferase-catalyzed reactions as well as decreasing the impact of undesirable variables.</p> |
申请公布号 |
EP2646548(A1) |
申请公布日期 |
2013.10.09 |
申请号 |
EP20110845321 |
申请日期 |
2011.12.05 |
申请人 |
GENE STREAM PTY LTD. |
发明人 |
DALY, JOHN;BROWNRIGG, LEON, MICHAEL;TIAO, JIM YU-HSIANG |
分类号 |
C12N9/02;C07K1/00;C07K2/00;C12Q1/66;G01N33/52 |
主分类号 |
C12N9/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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