发明名称 NOVEL COMPOUND AND MEDICAL USE THEREOF
摘要 <p>Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.</p>
申请公布号 EP2647619(A1) 申请公布日期 2013.10.09
申请号 EP20110844106 申请日期 2011.12.01
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 KOKUBO, MASAYA;YANO, KOJI
分类号 C07C229/36;A61K31/235;A61P25/16 主分类号 C07C229/36
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