发明名称 Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds
摘要 This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations.
申请公布号 US8552191(B2) 申请公布日期 2013.10.08
申请号 US20080531859 申请日期 2008.03.20
申请人 MERGELSBERG INGRID;SCHERER DOMINIK HERMANN;HUTTENLOCH MONIKA ERIKA;TSUI HON-CHUNG;PALIWAL SUNIL;SHIH NENG-YANG;OPKO HEALTH, INC. 发明人 MERGELSBERG INGRID;SCHERER DOMINIK HERMANN;HUTTENLOCH MONIKA ERIKA;TSUI HON-CHUNG;PALIWAL SUNIL;SHIH NENG-YANG
分类号 C07D221/20 主分类号 C07D221/20
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