发明名称 |
Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds |
摘要 |
This application discloses a novel process to synthesize 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compounds, which may be used, for example, as NK-1 inhibitor compounds in pharmaceutical preparations.
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申请公布号 |
US8552191(B2) |
申请公布日期 |
2013.10.08 |
申请号 |
US20080531859 |
申请日期 |
2008.03.20 |
申请人 |
MERGELSBERG INGRID;SCHERER DOMINIK HERMANN;HUTTENLOCH MONIKA ERIKA;TSUI HON-CHUNG;PALIWAL SUNIL;SHIH NENG-YANG;OPKO HEALTH, INC. |
发明人 |
MERGELSBERG INGRID;SCHERER DOMINIK HERMANN;HUTTENLOCH MONIKA ERIKA;TSUI HON-CHUNG;PALIWAL SUNIL;SHIH NENG-YANG |
分类号 |
C07D221/20 |
主分类号 |
C07D221/20 |
代理机构 |
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