发明名称 |
Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
摘要 |
Novel peptides that inhibit the release of microparticles from cells are disclosed. The peptide contains at least one VGFPV motif at the N-terminal and has a length of 10-100 amino acids. Also disclosed is polynucleotide encoding the peptide, expression vectors carrying the polynucleotide, and methods for treating AIDS and tumors using the novel peptides.
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申请公布号 |
US8551943(B2) |
申请公布日期 |
2013.10.08 |
申请号 |
US201213621597 |
申请日期 |
2012.09.17 |
申请人 |
BOND VINCENT CRAIG;POWELL MICHAEL;HUANG MING BO;ALI SYED;RAYMOND ANDREA D.;SHELTON MARTIN NEVILLE;VILLINGER FRANCOIS JEAN;MOREHOUSE SCHOOL OF MEDICINE |
发明人 |
BOND VINCENT CRAIG;POWELL MICHAEL;HUANG MING BO;ALI SYED;RAYMOND ANDREA D.;SHELTON MARTIN NEVILLE;VILLINGER FRANCOIS JEAN |
分类号 |
A61P31/12;A61K39/00;A61K39/21;A61P31/18;C12N5/22 |
主分类号 |
A61P31/12 |
代理机构 |
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代理人 |
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地址 |
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