发明名称 Pharmaceutical compositions of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid and administration thereof
摘要 A pharmaceutical composition comprising Compound 1, (3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid), and at least one excipient selected from: a filler, a diluent, a disintegrant, a surfactant, a binder, a glidant and a lubricant, the composition being suitable for oral administration to a patient in need thereof to treat a CFTR mediated disease such as Cystic Fibrosis. Methods for treating a patient in need thereof include administering an oral pharmaceutical formulation of Compound 1 to the patient.
申请公布号 US8552034(B2) 申请公布日期 2013.10.08
申请号 US201113081750 申请日期 2011.04.07
申请人 VERWIJS MARINUS JACOBUS;ALARGOVA ROSSITZA GUEORGUIEVA;KAUSHIK RITU ROHIT;KADIYALA IRINA NIKOLAEVNA;YOUNG CHRISTOPHER;VERTEX PHARMACEUTICALS INCORPORATED 发明人 VERWIJS MARINUS JACOBUS;ALARGOVA ROSSITZA GUEORGUIEVA;KAUSHIK RITU ROHIT;KADIYALA IRINA NIKOLAEVNA;YOUNG CHRISTOPHER
分类号 A61K31/443;C07D405/12 主分类号 A61K31/443
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