发明名称 |
Deuterated 3-(dihydro-1H-pyrazolo[4,3-D]pyrimidin-5-yl)-4-propoxybenzenesulfonamide derivatives and methods of use |
摘要 |
This invention relates to novel 3-(dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxybenzenesulfonamide compounds of Formula I: wherein each Y is independently selected from hydrogen and deuterium and at least one Y is deuterium, as well as to pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering inhibitors of cyclic guanosine 3',5'-monophosphate specific phosphodiesterase (cGMP-specific PDE), in particular PDE5.
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申请公布号 |
US8552008(B2) |
申请公布日期 |
2013.10.08 |
申请号 |
US20070876754 |
申请日期 |
2007.10.22 |
申请人 |
TUNG ROGER;CONCERT PHARMACEUTICALS, INC. |
发明人 |
TUNG ROGER |
分类号 |
C07D487/04;A61K31/519;A61P15/10 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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