Compuestos derivados de sulfonil-carbamoil-fenoxi-pirrolo-piridina, inhibidores de la actividad de proteinas anti-apoptoticas bcl-2; composicion farmaceutica; y metodo para tratar cancer de vejiga, cancer de cerebro, cancer de mama, cancer de medula osea, cancer cervical y leucemia linfocitica cronica, entre otras enfermedades.

摘要

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.