| 摘要 |
PURPOSE: An immunostimulatory composition containing liposome-encapsulated oligonucleotides as active ingredients is provided to prevent and treat various immune deficiency diseases and to be used as an immunoadjuvant. CONSTITUTION: An immunostimulatory composition contains liposome-encapsulated immunostimulatory oligonucleotides as active ingredients, containing dioleyl phosphatidylethanolamine (DOPE) and cholesteryl hemisuccinate (CHEMS). The immunostimulatory oligonucleotides are CpG oligonucleotides with a nucleotide sequence of sequence number 1 or CpT oligonucleotide with nucleotide sequences selected from sequence numbers 2-49. The immunostimulatory oligonucleotides are CpT oligonucleotides with nucleotide sequences selected among sequence numbers 2, 3, 4, 19, 24, 39, and 46-49. |
