发明名称 Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen
摘要 The present invention provides a method for treating multiple sclerosis (MS), and for reducing flu-like symptoms associated with administration of an interferon to a patient with MS. The method involves intramuscularly administering the interferon to the MS patient according to an escalating dosing regimen in weeks 1 to 3, and a full therapeutically effective dose of interferon in week 4. In one embodiment of the invention, the escalating dosing regimen comprises administering one quarter of the therapeutically effective dose in week 1, half of the therapeutically effective dose in week 2, and three-quarters of the therapeutically effective dose in week 3. Also provided are titration packages for enabling compliance with a regimen of changing dosage of an interferon over a period of time.
申请公布号 AU2012229104(A1) 申请公布日期 2013.10.03
申请号 AU20120229104 申请日期 2012.03.15
申请人 BIOGEN IDEC INC. 发明人 DEYKIN, AARON
分类号 A61K38/21;A61M5/00;A61P25/28 主分类号 A61K38/21
代理机构 代理人
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