| 发明名称 |
ANTI-SIGLEC15 ANTIBODY WITH MODIFIED CDR |
| 摘要 |
To provide an abnormal-bone-metabolism treatment and/or a prophylactic pharmaceutical composition targeting a protein coded for by a gene that is strongly expressed in osteoclasts. The provision, etc., of a pharmaceutical composition containing an antibody that specifically recognizes human SIGLEC15 and exhibits the effect of inhibiting the formation of osteoclasts. |
| 申请公布号 |
WO2013147213(A1) |
申请公布日期 |
2013.10.03 |
| 申请号 |
WO2013JP59654 |
申请日期 |
2013.03.29 |
| 申请人 |
DAIICHI SANKYO COMPANY,LIMITED |
发明人 |
HIRUMA, YOSHIHARU;KIMURA, TAKAKO;SHIMIZU, HIRONARI |
| 分类号 |
C12N15/09;A61K39/395;A61P1/02;A61P7/00;A61P19/00;A61P19/02;A61P19/10;A61P29/00;A61P35/00;A61P43/00;C07K16/18;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12P21/08 |
主分类号 |
C12N15/09 |
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