发明名称 |
PHOSPHODIESTERASE-4 INHIBITOR CAPABLE OF AVOIDING VOMIT REACTION AND PREPARATION METHOD FOR SAME |
摘要 |
The present invention relates to a phosphodiesterase-4 inhibitor capable of avoiding a vomit reaction. The phosphodiesterase-4 inhibitor is a compound, a prodrug or a solvate represented by DTPM. The name of DTPM is 1-(4-difluoro methoxy-3-(tetrahydrofuran-3-oxyl)phenyl)-3-dimethyl-1-ketone, and a chemical formula is shown in formula (I). The compound in the present invention can prepare a drug that can effectively weaken or even avoid an adverse reaction such as vomit, can treat depression and alzheimer disease and can improve cognitive competence. |
申请公布号 |
WO2013143259(A1) |
申请公布日期 |
2013.10.03 |
申请号 |
WO2012CN80974 |
申请日期 |
2012.09.04 |
申请人 |
XU, JIANGPING |
发明人 |
XU, JIANGPING;ZHOU, ZHONGZHEN;CHENG, YUFANG;ZHANG, MINGZI |
分类号 |
C07D307/20;A61K31/341;A61P25/24;A61P25/28 |
主分类号 |
C07D307/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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