发明名称 |
VACCINE COMPOSITION COMPRISING COMPLEXED IMMUNOSTIMULATORY NUCLEIC ACIDS AND ANTIGENS PACKAGED WITH DISULFIDE-LINKED POLYETHYLENEGLYCOL/PEPTIDE CONJUGATES |
摘要 |
The present invention is directed to an inventive composition or vaccine composition comprising a) an adjuvant component comprising or consisting of at least one immunostimulatory nucleic acid sequence, complexed with a complexing agent; b) an antigen, preferably a protein or peptide antigen and/or a nucleic acid sequence encoding said antigen; and c) a carrier molecule for combined packaging the adjuvant component and the antigen. The present invention is also directed to the first medical use of such an inventive composition or vaccine composition and to the second medical use of such an inventive composition or vaccine composition or components thereof for the treatment of diseases, such as infectious or cancer or tumour diseases as defined herein. The present invention furthermore discloses kits comprising such a composition or vaccine composition.
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申请公布号 |
US2013259879(A1) |
申请公布日期 |
2013.10.03 |
申请号 |
US201213824449 |
申请日期 |
2012.02.10 |
申请人 |
BAUMHOF PATRICK;KALLEN KARL-JOSEF;FOTIN-MLECZEK MARIOLA;CUREVAC GMBH |
发明人 |
BAUMHOF PATRICK;KALLEN KARL-JOSEF;FOTIN-MLECZEK MARIOLA |
分类号 |
A61K39/39 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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地址 |
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