发明名称 INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
摘要 The present invention provides compounds useful as agents for the prevention or treatment of a disease associated with abnormal serum uric acid level and the like. That is, the present invention relates to indolizine derivatives represented by the following formula (I) having xanthine oxidase inhibitory activities and useful as agents for the prevention or treatment of a disease associated with abnormality of serum uric acid level, prodrugs thereof, salts thereof or the like. In the formula, ring U represents aryl or heteroaryl; R 1 represents halogen, a hydroxy group or the like; R 2 represents halogen, a hydroxy group, alkyl, alkoxy, alkyl substituted by fluorine, alkoxy substituted by fluorine or the like; m represents a number from 0 to 2; n represents a number from 0 to 3; and R 3 represents hydrogen, fluorine or the like.
申请公布号 PT2415771(E) 申请公布日期 2013.10.03
申请号 PT20100758713T 申请日期 2010.03.30
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 KAZUO SHIMIZU;YASUSHI TAKIGAWA;MASATOI IZUKA
分类号 C07D471/04;A61K31/437;A61P13/02;A61P13/12;A61P19/02;A61P19/06;A61P43/00 主分类号 C07D471/04
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