发明名称 |
POLYAMINE TRANSPORT SELECTIVE THERAPEUTIC AGENTS WITH ENHANCED STABILITY |
摘要 |
Disclosed herein are di-substituted aryl polyamine compounds and methods of making and using the same. The di-substituted polyamine compounds act as PTS targeting agents, which selectively target the polyamine transport system (PTS) with high efficacy and have improved stability in the presence of amine oxidases. |
申请公布号 |
WO2013148230(A1) |
申请公布日期 |
2013.10.03 |
申请号 |
WO2013US31166 |
申请日期 |
2013.03.14 |
申请人 |
UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.;PHANSTIEL IV, OTTO;MUTH, AARON |
发明人 |
PHANSTIEL IV, OTTO;MUTH, AARON |
分类号 |
A61K31/13;A61K31/137;A61P35/00 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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